Listed by Celia Taylor of Option One Real Estate
Exceptional opportunity to acquire 4.756 acres with both residential and commercial zoning on a frontage road in one of the fastest-growing corridors just minutes from San Antonio. With outstanding development potential, excellent visibility, and flexible zoning, this property is well-suited for a variety of commercial, mixed-use, or investment opportunities, subject to applicable zoning and permitting requirements. The value of the two existing homes are not being considered in the pricing and are being sold AS IS, with the primary value in the land. The level, wooded acreage features mature native trees and offers the flexibility to clear for development or incorporate the natural landscape into your project. Strategically located with convenient access to Loop 1604 and Highway 281, the property's frontage road location provides excellent accessibility and exposure, along with strong connectivity to major employment centers, established residential communities, and a growing customer base. Conveniently located near San Antonio's growing South Side employment corridor, offering easy access to major employers including Toyota Motor Manufacturing, HOLT CAT, TJ Maxx Distribution Center, pharmaceutical manufacturers, healthcare facilities, and numerous logistics and industrial employers-making this an ideal location for commuters.

Listing Tools

Property Details of 25365 Us Highway 281 S

Property Details

Map Location

Based on information submitted to LERA MLS as of July 15, 2026 9:33 AM UTC . All data is deemed reliable but is not guaranteed accurate by the MLS. All information should be independently reviewed and verified for accuracy. IDX information is provided exclusively for consumers’ personal, noncommercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.

Hi there! How can we help you?

Contact us using the form below or give us a call.

Send Us A Message:

I agree to receive marketing and customer service calls and text messages from Meka Durham-Honer. To opt out, you can reply 'stop' at any time or click the unsubscribe link in the emails. Consent is not a condition of purchase. Msg/data rates may apply. Msg frequency varies. Privacy Policy.

Do not fill in this field:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Hi there! How can we help you?

Contact us using the form below or give us a call.

Send Us A Message:

Do not fill in this field:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Hi there! How can we help you?

Contact us using the form below or give us a call.

Send Us A Message:

Do not fill in this field:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Do not fill in this field:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Do not fill in this field:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Do not fill in this field:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

$

Do not fill in this field:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.